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NRx Pharmaceuticals, Lotus Pharmaceuticals and Alvogen Inc. Announce Collaboration to Develop and Commercialize NRX-101

NRx Pharmaceuticals, Lotus Pharmaceuticals and Alvogen Inc. Announce Collaboration to Develop and Commercialize NRX-101

NRx Pharmaceuticals Unveils potential Treatment for Suicidal Thoughts and Depression

On November 16th, 2023 Dr. Jonathan Javitt joined Steve Darling from Proactive to discuss groundbreaking developments in the treatment of suicidal ideation and depression.

NRx Pharmaceuticals Unveils potential Treatment for Suicidal Thoughts and Depression

On November 16th, 2023 Dr. Jonathan Javitt joined Steve Darling from Proactive to discuss groundbreaking developments in the treatment of suicidal ideation and depression.

Hope for people with life-threatening depression and PTSD

NRx is developing breakthrough medicines for people with life-threatening depression and PTSD. Our lead candidate, NRx-101, is the first oral medication in FDA trials for suicidal bipolar depression.

Hope for people with life-threatening depression and PTSD

NRx is developing breakthrough medicines for people with life-threatening depression and PTSD. Our lead candidate, NRx-101, is the first oral medication in FDA trials for suicidal bipolar depression.

Dawson James Securities and Senior Management discuss the history and foundations of NRx Pharmaceuticals.

Addressing the Unmet Medical Need in Suicidality as a Result of Bipolar Depression, PTSD and Related Indications

Dawson James Securities and Senior Management discuss the history and foundations of NRx Pharmaceuticals.

Addressing the Unmet Medical Need in Suicidality as a Result of Bipolar Depression, PTSD and Related Indications

Every 27 seconds someone in the U.S. attempts suicide

11-20% of people with bipolar disorder will die by suicide

0 Approved drugs exist today for suicidal bipolar depression

NRx-101 is the first investigational drug in FDA trials for suicidal bipolar depression, awarded fast track designation, breakthrough therapy designation, and a special protocol agreement by the FDA. Positive Phase 2 data*. Phase 3 data expected 2023.

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As many as 50% of individuals with bipolar disorder attempt suicide or have serious thoughts of suicide and between 11-20% of those attempt and succumb to suicide.





Source:
Pallaskorpi, et al. “Incidence and predictors of suicide attempts in bipolar I and II disorders: A 5-year follow-up study,” Bipolar Disorders, 2016
“Suicide Attempts and Completions in Patients With Bipolar Disorder,” Psychiatric Times, 2007

NRX-101 is an investigational treatment for bipolar depression in patients with Acute and Sub-Acute Suicidal Ideation and Behavior (ASIB, SSIB)

Our Science: Targeting The NMDA Receptor

The brain’s NMDA receptor is a newly validated target for treating suicidal ideation and depressive symptoms.

Our Pipeline

We are investigating our non-hallucinogenic, non-addictive, non-neurotoxic approach to NDMA inhibition for suicidal bipolar depression and PTSD.

Patient Stories & Resource

We’re bringing hope to life for people with severe bipolar depression and PTSD, and we are currently investigating our approach in ongoing clinical trials.

Our Company

NRx is a clinical biopharma company focused on the high unmet need for lifesaving treatments for people with severe bipolar depression and PTSD in the presence of suicidality.